Holter W, Hajek-Rosenmayr A, Mayr W R
Wien Klin Wochenschr. 1983 Sep 30;95(18):643-5.
Lymphocytes from HLA-identical unrelated donors often show positive stimulation in the mixed lymphocyte culture, possibly caused by alleles of HLA-linked, but not yet defined gene loci. In order to investigate such determinants lymphocytes from HLA-DR identical individuals were primed and tested in the PLT system. Family and population data indicate that such antigens exist and can be detected in vitro.
来自 HLA 相同的无关供者的淋巴细胞在混合淋巴细胞培养中常显示出阳性刺激，这可能是由 HLA 连锁但尚未明确的基因座的等位基因引起的。为了研究此类决定因素，对来自 HLA-DR 相同个体的淋巴细胞进行了预处理，并在 PLT 系统中进行了检测。家族和群体数据表明此类抗原存在且可在体外检测到。
