Gelmini G, Dall'Asta D, Artioli F, Pedrazzoni M, Ferretti P
Acta Biomed Ateneo Parmense. 1983;54(4):311-7.
In two groups of subjects (young and elderly), the red blood cell (RBC) deformability was examined determining the filtration time by means of two different methods (filtration of whole blood and filtration of RBC suspension with hematocrit adjusted at 20%, respectively). In addition, the DFE (Debit de filtration erythrocytaire), an indirect index of capillary blood flow, was mathematically derived. Since the filtration times appear to be positively correlated with age, it is conceivable that in the elderly, erythrocytes are less deformable than in the young, and that this change may impair both capillary blood flow and tissue oxygen delivery; this alteration is further emphasized when the relationship between whole blood filtration time and hematocrit is taken into account.
在两组受试者（年轻人和老年人）中，通过两种不同方法（分别为全血过滤和血细胞比容调整为20%的红细胞悬液过滤）测定过滤时间来检查红细胞（RBC）变形性。此外，还通过数学推导得出了DFE（红细胞过滤率），这是毛细血管血流的一个间接指标。由于过滤时间似乎与年龄呈正相关，可以想象，老年人的红细胞比年轻人的红细胞变形性更差，这种变化可能会损害毛细血管血流和组织氧输送；当考虑全血过滤时间与血细胞比容之间的关系时，这种改变会更加明显。
