Booth P B
Vox Sang. 1978;34(4):212-20. doi: 10.1111/j.1423-0410.1978.tb02470.x.
Two different Melanesian antibodies demonstrated, by blocking tests and their reaction patterns, steric interaction of S, s and U components. The antigen(s) detected, designated Ux and Uz, may represent differing conformations, genetically determined, of certain U, S and s structures. Of 1,000 Caucasian bloods, 3 had very marked enhancement of Ux. Family studies are presented. In one such blood, abnormal steric interaction of D with s and U was indicated. Melanesian population studies show that Ux and Uz are among the antigens depressed in recessive ovalocytosis. The linkage disequilibria affecting MNSs and SsUz are inter-related, the associations being of SUz with Caucasian M and Melanesian N.
两种不同的美拉尼西亚抗体通过阻断试验及其反应模式证明了S、s和U成分的空间相互作用。检测到的抗原（称为Ux和Uz）可能代表某些U、S和s结构的不同构象，这些构象由基因决定。在1000份白种人血液中，有3份Ux有非常明显的增强。文中呈现了家族研究。在其中一份这样的血液中，表明D与s和U存在异常的空间相互作用。美拉尼西亚人群研究表明，Ux和Uz是隐性椭圆形红细胞增多症中受抑制的抗原之一。影响MNSs和SsUz的连锁不平衡是相互关联的，关联表现为SUz与白种人的M以及美拉尼西亚人的N相关。
