异丙肾上腺素所致实验性心肌损伤的形态生理学研究。注释I. 形态学方面。
Morphophysiological studies in experimental myocardial aggressions with isoproterenol. Note I. Morphological aspects.
作者信息
Laky D, Constantinescu S, Filipescu G, Ratea E, Zeană C
出版信息
Morphol Embryol (Bucur). 1983 Oct-Dec;29(4):273-7.
PMID:6228730
Abstract
The morphopathogenesis of lesions induced by high doses of isoproterenol injected for 1-7 days and 1-3 months is dynamically studied in groups of Wistar rats and guinea pigs. The disseminated myocardial necroses induced were of a hypoxic nature. By cicatricial substitutions, lesions of cardiosclerosis similar to those observed in pheochromocytoma cases were obtained.
摘要
在Wistar大鼠和豚鼠组中，动态研究了连续1 - 7天及1 - 3个月注射高剂量异丙肾上腺素所诱导病变的形态发病机制。所诱导的弥漫性心肌坏死具有缺氧性质。通过瘢痕替代，获得了与嗜铬细胞瘤病例中观察到的类似的心硬化病变。
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