[Cryoglobulinemias].

Cryoglobulins are serum proteins which precipitate at 4 degrees C and redissolve during warming. When purified, they can be divided by immunochemical analysis into three main groups: monoclonal cryoglobulin, mixed cryoglobulin containing a monoclonal immunoglobulin, and polyclonal mixed cryoglobulins. There is a close correlation between the immunochemical composition of cryoglobulins and the symptoms or diseases associated with their presence.