Hall D, Gruentzig A
AJR Am J Roentgenol. 1984 Jan;142(1):13-6. doi: 10.2214/ajr.142.1.13.
Atherosclerotic coronary artery disease is a progressive process for which effective palliative methods have been developed. The evolution of surgical bypass grafting over the past two decades now permits its application to most symptomatic patients. In 1977 an alternative, transluminal angioplasty, was first performed in man and has become widely accepted. Advanced radiographic equipment is required for adequate visual control of the placement of catheters, guide wires, and balloons. Careful manipulation of catheters is crucial to success and safety. Procedural details and proper follow-up are described. While a discrete stenotic lesion in a proximal single vessel is the ideal indication, some patients with double-vessel disease are now being accepted. In a personal experience of 2000 cases, successful dilatation was achieved in 88%. Emergency bypass surgery was required in 3.3%. Myocardial infarction occurred in 1.2%, and there were two deaths. In a larger, multiinstitutional study, the primary success rate has averaged 61%. Recurrent stenosis occurs in about 30%; redilatation is possible. Some perspectives about this effective, nonsurgical alternative are offered, including its potential for massive savings in the cost of handling obstructive coronary artery disease.
动脉粥样硬化性冠状动脉疾病是一个渐进的过程,针对这一疾病已开发出有效的姑息治疗方法。在过去二十年中,外科搭桥手术不断发展,如今已可应用于大多数有症状的患者。1977年,一种替代方法——经皮腔内血管成形术首次应用于人体,并已被广泛接受。进行导管、导丝和球囊置入时,需要先进的放射设备进行充分的可视化控制。导管的精细操作对成功和安全至关重要。文中描述了操作细节和适当的随访情况。虽然近端单支血管中的孤立性狭窄病变是理想的适应症,但现在一些双支血管病变的患者也被纳入治疗。根据个人2000例的经验,成功扩张率为88%。3.3%的患者需要进行急诊搭桥手术。心肌梗死发生率为1.2%,有两例死亡。在一项更大规模的多机构研究中,主要成功率平均为61%。再狭窄发生率约为30%;可以再次扩张。文中提供了关于这种有效的非手术替代方法的一些观点,包括其在处理阻塞性冠状动脉疾病成本方面可能大幅节省的潜力。