Nordlind K, Henze A
Int Arch Allergy Appl Immunol. 1984;73(2):162-5. doi: 10.1159/000233458.
Mercuric chloride and, to a lower extent, nickel sulfate, stimulated DNA synthesis of both thymocytes and peripheral blood lymphocytes. The metal allergens stimulated both cell types at a lower degree than lectinic mitogens (PHA, Con A and PWM) did. In peripheral blood lymphocytes the stimulation degree was higher than in thymocytes after addition of metal allergens as well as lectinic mitogens. The presence of serum seemed to have a protective and potentiating role regarding the effect of mercuric chloride and lectinic mitogens, the effect of nickel sulfate being mainly unchanged. With increasing age of the individuals, an increase in the stimulation degree with mercuric chloride and lectinic mitogens was indicated, while nickel sulfate gave a decrease.
氯化汞以及程度稍低的硫酸镍，刺激了胸腺细胞和外周血淋巴细胞的DNA合成。金属过敏原对这两种细胞类型的刺激程度低于凝集素促细胞分裂剂（PHA、Con A和PWM）。在加入金属过敏原以及凝集素促细胞分裂剂后，外周血淋巴细胞的刺激程度高于胸腺细胞。血清的存在似乎对氯化汞和凝集素促细胞分裂剂的作用具有保护和增强作用，而硫酸镍的作用基本不变。随着个体年龄的增加，氯化汞和凝集素促细胞分裂剂的刺激程度有所增加，而硫酸镍的刺激程度则有所下降。
