基于知识的λ噬菌体基因调控模拟。
Knowledge-based simulation of genetic regulation in bacteriophage lambda.
作者信息
Meyers S, Friedland P
出版信息
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 1):1-9. doi: 10.1093/nar/12.1part1.1.
Abstract
We have developed a general-purpose computer program for the functional simulation of regulatory genetics. This simulator is knowledge-based and was developed using the Unit System, a software tool for the acquisition, representation, and manipulation of hierarchically organized knowledge. The advantages of a knowledge-based design are presented, and the simulator's architecture is described. Its performance on the decision between lytic and lysogenic growth in Bacteriophage Lambda is reported.
摘要
我们开发了一个用于调控遗传学功能模拟的通用计算机程序。该模拟器基于知识，是使用单元系统开发的，单元系统是一种用于获取、表示和处理层次组织知识的软件工具。本文介绍了基于知识设计的优势，并描述了模拟器的架构。报告了其在噬菌体λ裂解生长和溶原生长之间决策方面的性能。
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