Arrago J P, Rain J D, Rocher F, Vigneron N, Pecking A, Najean Y
Presse Med. 1984 Feb 4;13(4):209-13.
One-hundred and twenty patients with sicca syndrome, connective tissue disease or chronic graft-versus-host disease were investigated in the Saint-Louis Hospital Department of Nuclear Medicine. Technetium scanning of the salivary glands was performed in all patients. The results of the scintigraphic study were closely correlated with clinical and histological data in patients with Sjögren's syndrome. This method, which accurately quantifies the salivary function without danger nor discomfort to the patients, has a number of advantages: (a) it is sensitive enough to detect minimal salivary gland dysfunction; (b) it differentiates between parotid gland and submandibular gland involvement and demonstrates asymmetry in pathological processes; (c) it helps in following up patients with Sjögren's disease and in assessing the results of immunosuppressive or anti-inflammatory treatment.
圣路易医院核医学科对120例患有干燥综合征、结缔组织病或慢性移植物抗宿主病的患者进行了调查。所有患者均进行了唾液腺锝扫描。闪烁显像研究结果与干燥综合征患者的临床和组织学数据密切相关。这种方法能准确量化唾液功能，对患者无危险且无不适，有诸多优点：(a) 灵敏度足以检测出轻微的唾液腺功能障碍；(b) 可区分腮腺和下颌下腺受累情况，并显示病理过程中的不对称性；(c) 有助于对干燥综合征患者进行随访，并评估免疫抑制或抗炎治疗的效果。
