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[分枝杆菌病]

[Mycobacterioses].

作者信息

Grosset J, Sors C

出版信息

Presse Med. 1984 Feb 4;13(4):215-8.

PMID:6229761
Abstract

Mycobacteriosis are opportunistic infections caused by atypical mycobacteria. These have microscopic features resembling those of tubercle bacillus but differ in their cultural and biochemical characteristics and above all, their resistance to antituberculous antibiotics. The lesions chiefly involve the lungs, the lymph nodes or the skin and usually mimick those of tuberculosis. The diagnosis rests on repeated isolation in pathological specimens of the same atypical mycobacterium with a sufficient number of colonies, or on its sole presence in effusion fluids, biopsies or surgical specimens. Treatment with antibiotics is disappointing, except for M. kansasii. Surgical treatment can only be considered in those exceptional cases when the patient is young, has limited lesions and is not immuno-depressed.

摘要

分枝杆菌病是由非典型分枝杆菌引起的机会性感染。这些细菌具有类似于结核杆菌的微观特征,但在培养和生化特性方面有所不同,最重要的是,它们对抗结核抗生素具有耐药性。病变主要累及肺部、淋巴结或皮肤,通常与结核病相似。诊断依赖于在病理标本中反复分离出具有足够数量菌落的同一非典型分枝杆菌,或仅在积液、活检或手术标本中发现该菌。除堪萨斯分枝杆菌外,抗生素治疗效果不佳。只有在患者年轻、病变有限且无免疫抑制的特殊情况下,才考虑手术治疗。

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