异丙托溴铵与茶碱联合治疗哮喘
Combined therapy with ipratropium and theophylline in asthma.
作者信息
Kreisman H, Cohen C, Ghezzo H, Vickerson F, Frank H, Wolkove N
出版信息
Ann Allergy. 1984 Feb;52(2):90-3.
PMID:6230034
Abstract
Ipratropium (40 micrograms) and theophylline (oxtriphylline 400 mg) were administered to 24 asthmatics in a randomized double-blind placebo controlled trial. The combination of these agents produced additive bronchodilation for up to two hours, with a 23 percent maximal increase in FEV1. This regimen promises to be safe, effective therapy for patients with asthma.
摘要
在一项随机双盲安慰剂对照试验中，对24名哮喘患者给予异丙托溴铵（40微克）和茶碱（多索茶碱400毫克）。这些药物联合使用可产生长达两小时的相加性支气管扩张作用，第一秒用力呼气量（FEV1）最大增加23%。该治疗方案有望成为哮喘患者安全、有效的治疗方法。
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