植物血凝素对IgE反应的调节作用。
Modulation of IgE response by phytohemagglutinin.
作者信息
Astorquiza M I, Sayago S
出版信息
Int Arch Allergy Appl Immunol. 1984;73(4):367-9. doi: 10.1159/000233500.
PMID:6230320
Abstract
The effect of the administration of phytohemagglutinin (PHA) on the IgE response was studied. RF mice were immunized with OA in aluminum hydroxide gel and PHA was injected 1 or 2 days before the immunization in doses of 80 or 1 microliter. Results show that PHA injected on day -1 induces suppression and PHA administered on day -2 induces some stimulation in the IgE response. This effect is independent of the PHA doses used and does not affect the anti-OA hemagglutinin production.
摘要
研究了注射植物血凝素（PHA）对IgE反应的影响。用氢氧化铝凝胶中的卵清蛋白（OA）对RF小鼠进行免疫，并在免疫前1天或2天以80或1微升的剂量注射PHA。结果表明，在第-1天注射PHA会诱导抑制作用，而在第-2天注射PHA会在IgE反应中诱导一定的刺激作用。这种效应与所用的PHA剂量无关，且不影响抗OA血凝素的产生。
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