噬菌体T1在噬菌体λ的P基因和Q基因之间的位点启动DNA包装。
Initiation by bacteriophage T1 of DNA packaging at a site between the P and Q genes of bacteriophage lambda.
作者信息
Drexler H
出版信息
J Virol. 1984 Mar;49(3):754-9. doi: 10.1128/JVI.49.3.754-759.1984.
Abstract
The growth of phage T1 on cells tandemly lysogenic for heteroimmune lambdoid prophages leads to a nonrandom packaging of lambda DNA by T1. A site, called esp-lambda, is located between the P and Q genes of lambda and results in increased packaging to the left by T1. When cloned into pBR322, the esp-lambda site causes a significant increase in transduction of the plasmid by T1. The nin5 deletion inactivates esp-lambda.
摘要
噬菌体T1在对异源免疫性λ样原噬菌体呈串联溶原状态的细胞上生长，会导致T1对λDNA进行非随机包装。一个名为esp-λ的位点位于λ的P基因和Q基因之间，会导致T1向左的包装增加。当克隆到pBR322中时，esp-λ位点会使T1对该质粒的转导显著增加。nin5缺失会使esp-λ失活。
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