Guerrini M, Vittoria A, Pieragalli D, Acciavatti A, Del Bigo C, Martelli G, Franchi M, Messa G, Galigani C, Di Perri T
Ric Clin Lab. 1983;13 Suppl 3:309-14.
The aim of this study was to evaluate the possible action in vitro of the platelets on the rheological behavior of red blood cells in healthy subjects and in patients with peripheral obliterative arterial disease before and after an isotonic exercise. Red blood cells and platelets from control subjects and from patients were tested in several ratios before and after the exercise studying the erythrocyte filterability. beta-thromboglobulin, a platelet-specific protein, was determined in vivo in all subjects before and after the exercise and in vitro as percent of increase between PPP and PRP activated, to monitor the platelet release. The results showed the interrelationship between platelet activation and rheological behavior of red blood cells.
本研究的目的是评估在等张运动前后，健康受试者以及外周闭塞性动脉疾病患者体内血小板对红细胞流变学行为可能产生的体外作用。在运动前后，以不同比例对对照组受试者和患者的红细胞与血小板进行检测，研究红细胞过滤性。在运动前后对所有受试者体内血小板特异性蛋白β-血小板球蛋白进行测定，并在体外测定PPP和PRP激活后增加的百分比，以监测血小板释放。结果显示了血小板活化与红细胞流变学行为之间的相互关系。
