Grønlund J
Eur J Appl Physiol Occup Physiol. 1984;52(2):167-72. doi: 10.1007/BF00433387.
A new method for breath-to-breath determination of the oxygen flux across the alveolar membrane is described. The principle of the method is to integrate the product of oxygen concentration and flow in the respiratory gas over an interval, which covers a complete respiratory cycle. The result is corrected for the change in oxygen content of the lungs through a formula, which, in contrast to those used in other methods, is independent of the residual capacity of the lungs. The method was evaluated with respect to repeatability by repetitive measurement of oxygen flux in twenty volunteer subjects, and with respect to accuracy by comparing the measured oxygen fluxes with those obtained by the gas collection method. The coefficient of variation was found to be 8% and the breath to breath determinations were, on an average, 6% lower than those of the gas collection method.
本文描述了一种用于逐次呼吸测定通过肺泡膜氧通量的新方法。该方法的原理是在一个涵盖完整呼吸周期的时间段内，对呼吸气体中氧气浓度与流量的乘积进行积分。通过一个公式对肺部氧气含量的变化进行校正，该公式与其他方法中使用的公式不同，它与肺残气量无关。通过对20名志愿者进行重复测量来评估该方法的重复性，并通过将测量得到的氧通量与气体收集法获得的氧通量进行比较来评估其准确性。结果发现变异系数为8%，逐次呼吸测定结果平均比气体收集法低6%。
