Davison K
Psychiatr Dev. 1983 Spring;1(1):1-33.
This review aims to collate some of the extensive literature on the schizophrenia-like psychoses occurring in association with organic cerebral disorders. Their relationship to "true' schizophrenia is considered clinically, genetically and conceptually. The conclusions reached are as follows: The association of many organic cerebral disorders with schizophrenia exceeds chance expectation. Although there may be group differences, these psychoses include a range of symptoms similar to those found in the general run of psychoses diagnosed as schizophrenia. These psychoses usually occur in patients without genetic loading for schizophrenia. Organic cerebral disorder occurs in a substantial minority of patients diagnosed as schizophrenic and is of particular importance in the psychoses of childhood and old age. The site of the brain lesion is more important than the predisposition of the patient in the genesis of these psychoses, and lesions in the temporal lobe and diencephalon are of particular significance.
本综述旨在整理一些关于与器质性脑疾病相关的精神分裂症样精神病的大量文献。从临床、遗传和概念层面探讨了它们与“真性”精神分裂症的关系。得出的结论如下：许多器质性脑疾病与精神分裂症的关联超出了偶然预期。尽管可能存在群体差异，但这些精神病包括一系列与一般诊断为精神分裂症的精神病中发现的症状相似的症状。这些精神病通常发生在没有精神分裂症遗传负荷的患者中。器质性脑疾病在被诊断为精神分裂症的患者中占相当少数，在儿童期和老年期的精神病中尤为重要。在这些精神病的发生过程中，脑病变部位比患者的易感性更重要，颞叶和间脑的病变尤为显著。
