Lu Ying, Tian Yu, Gan Yu, Fu Yixiao, Chen Qibin, Zou Lei, Zhao Bangshu, Yan Yu, Liu Shudong, Chen Xiaolu, Li Xiao
Department of the First Clinical Medicine, Chongqing Medical University, Chongqing 400016, China.
Department of Psychiatry, Chongqing Eleventh People's, Chongqing 400038, China.
Brain Sci. 2022 Oct 15;12(10):1393. doi: 10.3390/brainsci12101393.
Electroconvulsive therapy (ECT) is an effective therapy for many psychiatric illnesses. However, intracranial occupying lesions are a relative contraindication to ECT. Arachnoid cysts are benign, congenital, and space-occupying lesions. Our study aimed to evaluate the efficacy and tolerability of ECT in psychiatric patients with arachnoid cysts. We retrospectively identified 62 psychiatric patients with arachnoid cysts; 43 of them underwent ECT and 19 did not. Their conditions were assessed by CGI-S and different scales depending on different diagnoses (PANSS for schizophrenia; HAMD for depression; YMRS for bipolar disorder). The side effect was assessed by TESS. Significant differences were shown in the reduced scores of the CGI-S between patients who underwent ECT and those who did not ( = 0.001), while, at the same time, there was no significant difference in their TESS score ( = 0.297). The current study found that ECT is an effective and tolerable therapy for psychiatric patients with arachnoid cysts.
电休克治疗（ECT）是治疗多种精神疾病的有效方法。然而，颅内占位性病变是ECT的相对禁忌证。蛛网膜囊肿是良性、先天性的占位性病变。我们的研究旨在评估ECT对患有蛛网膜囊肿的精神病患者的疗效和耐受性。我们回顾性地确定了62例患有蛛网膜囊肿的精神病患者；其中43例接受了ECT治疗，19例未接受。根据不同诊断，通过临床总体印象量表（CGI-S）和不同量表评估他们的病情（精神分裂症用阳性和阴性症状量表（PANSS）；抑郁症用汉密尔顿抑郁量表（HAMD）；双相情感障碍用杨氏躁狂量表（YMRS））。通过治疗中出现的症状量表（TESS）评估副作用。接受ECT治疗的患者与未接受ECT治疗的患者在CGI-S评分降低方面存在显著差异（P = 0.001），而与此同时，他们的TESS评分没有显著差异（P = 0.297）。当前研究发现，ECT对患有蛛网膜囊肿的精神病患者是一种有效且耐受性良好的治疗方法。
