Magnani G, Campari M, Ferrari C, Ghinelli F, Pelò A, Rotelli P G
Acta Biomed Ateneo Parmense. 1984;55(1):49-57.
An epidemiological survey of hepatitis B virus infection has been carried out in medical and paramedical employees of the Hospital of Parma, in order to identify high-risk groups and to estimate how many of subjects might be immunized with newly available but expansive vaccine. Radioimmunoassay procedures were used to detect the hepatitis B surface antigen (HBsAg) and the corresponding antibody (anti-HBs) in serum samples from 1682 hospital workers. Among these person tested, HBsAg was present in 57 (3.4%) and anti-HBs in 438 (26.3%); at least one of the two markers was found in 495 (29.4%). The prevalence of HBsAg and anti-HBs was related more closely to age, years and kind of occupation, than to clinical service (i.e. renal dialysis or medical services) and title (physician, nurse, laboratory technician, support staff.
为了确定高危人群,并评估有多少受试者可能接种新上市但价格昂贵的疫苗,帕尔马医院对医护人员及医辅人员进行了一项乙肝病毒感染的流行病学调查。采用放射免疫分析程序检测了1682名医院工作人员血清样本中的乙肝表面抗原(HBsAg)和相应抗体(抗-HBs)。在这些接受检测的人员中,57人(3.4%)存在HBsAg,438人(26.3%)存在抗-HBs;495人(29.4%)至少检测到这两种标志物中的一种。HBsAg和抗-HBs的流行率与年龄、工作年限和职业种类的关系,比与临床科室(如肾透析或医疗科室)及职称(医生、护士、检验技师、辅助人员)的关系更为密切。