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[胃黏膜的G1和G2抑素]

[G1 and G2 chalones of the gastric mucosa].

作者信息

Aruin L I, Smotrova I A, Gorodinskaia V S

出版信息

Biull Eksp Biol Med. 1984 Apr;97(4):455-7.

PMID:6232965
Abstract

A study was made of the action of human gastric mucosa G1 and G2 chalones on cellular regeneration of mouse gastric mucosa and of the duration of their maximal effect. Chalone fractions were obtained from the mucous membranes of 21 stomachs resected for peptic ulcer by the method of fractional ethanol precipitation. The data indicate that the maximal inhibitory action of G1 chalone occurs in 3, whereas that of chalone G2 in 6 hours. Some specificity of the action of chalones was discovered depending on the part of the gastric mucosa from which they were obtained.

摘要

对人胃黏膜G1和G2抑素对小鼠胃黏膜细胞再生的作用及其最大效应持续时间进行了研究。通过分级乙醇沉淀法从21例因消化性溃疡切除的胃黏膜中获得抑素组分。数据表明,G1抑素的最大抑制作用出现在3小时,而G2抑素的最大抑制作用出现在6小时。发现抑素的作用存在一定特异性,这取决于它们所取自的胃黏膜部位。

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