Alcan K E, Stertzer S H, Wallsh E, Bruno M S, DePasquale N P
Crit Care Med. 1984 Jun;12(6):489-95. doi: 10.1097/00003246-198406000-00004.
Retrospective analysis revealed that intra-aortic balloon counterpulsation was attempted in 321 patients at our institute from August 1, 1974, to July 1, 1982. The intra-aortic balloon pump (IABP) was successfully inserted in 298 cases (93%). Indications for an IABP included: cardiogenic shock (84 cases), preoperative hemodynamic coverage (15 cases), low-output syndrome (73 cases), pre- and postinfarction angina (75 cases), intractable congestive heart failure (12 cases), refractory ventricular arrhythmia (9 cases), percutaneous transluminal coronary angioplasty (14 cases), cardiac arrest (7 cases), and a miscellaneous group (9 cases). The overall major complication rate was 9%. The data from this experience support aggressive management of cardiogenic shock, i.e., early balloon insertion, angiography, and cardiac surgery, which significantly increases the survival rate (83%) over medical therapy combined with balloon counterpulsation alone. The IABP was also extremely effective in managing other high-risk categories when combined with some form of definitive mechanical correction, e.g., coronary revascularization, valve replacement, or percutaneous transluminal coronary angioplasty. Left ventricular (LV) function was a significant indicator of long-term survival in our series. Patients with normal or moderately impaired LV function had higher survival rates (95% and 82%, respectively) than patients with poor LV function (42%).
回顾性分析显示,1974年8月1日至1982年7月1日期间,我院对321例患者尝试进行主动脉内球囊反搏治疗。主动脉内球囊泵(IABP)成功植入298例(93%)。IABP的应用指征包括:心源性休克(84例)、术前血流动力学支持(15例)、低心排血量综合征(73例)、心肌梗死前后心绞痛(75例)、难治性充血性心力衰竭(12例)、难治性室性心律失常(9例)、经皮腔内冠状动脉成形术(14例)、心脏骤停(7例)以及其他杂项(9例)。总体主要并发症发生率为9%。该经验数据支持对心源性休克进行积极治疗,即早期植入球囊、血管造影和心脏手术,与单纯药物治疗联合球囊反搏相比,这显著提高了生存率(83%)。当与某种形式的确定性机械矫正(如冠状动脉血运重建、瓣膜置换或经皮腔内冠状动脉成形术)联合应用时,IABP在治疗其他高危类别方面也极其有效。在我们的系列研究中,左心室(LV)功能是长期生存的重要指标。左心室功能正常或轻度受损的患者生存率较高(分别为95%和82%),高于左心室功能较差的患者(42%)。