[Effect of the polymerase activity of DNA polymerase I on the development of the temperate bacteriophages Mu, lambda red- and lambda red-gam-. I. The effect of the polymerase activity of DNA polymerase I on the development of bacteriophages lambda red- and lambda red-gam-].

Phages lambda c1857 red3 and lambda bio10 in Escherichia coli K-12 cells with impaired function of DNA-polymerase I polymerizing activity are shown to restore their normal development level when exonucleases V and I are removed from cells. In other words, an indirect involvement of DNA-polymerase I in the development of phages lambda defective in general recombination systems and gene gam functions has been established. A probability of DNA-polymerase I participation in the recombination stage of phage lambda development in E. coli K-12 cells is discussed.