Schranz W, Kalden J R
Fortschr Med. 1984 Apr 26;102(16):458-62.
By experienced specialists plasma separation can be applied without any serious complications. It can be expected that in future specific principles of plasmapheresis for the elimination of pathogenetic agents will be developed. Even if the exact mechanism of action of this therapeutical principle is is not yet known in all details, plasma separation is indicated as a therapeutic emergency measure in patients with autoaggressive diseases especially in case the patient is endangered by marked progression of the disease and by the failure of conservative therapy with immunosuppressive agents. So far we have treated 48 patients with 206 plasma exchanges, most ot them because of immune diseases such as systemic lupus erythematodes and immunvascultits .
经验丰富的专家进行血浆分离时不会出现任何严重并发症。可以预期，未来将制定用于清除致病因子的血浆置换具体原则。即使这种治疗原则的确切作用机制尚未完全明确，但对于患有自身攻击性疾病的患者，尤其是当患者因疾病明显进展和免疫抑制剂保守治疗失败而面临危险时，血浆分离被视为一种紧急治疗措施。到目前为止，我们已对48例患者进行了206次血浆置换，其中大多数是由于免疫疾病，如系统性红斑狼疮和免疫性血管炎。
