[Disorders of contractile function and adrenoreactivity of the portal vein in emotionally-painful stress and experimental myocardial infarct and their prevention by means of membrane protectors].

The effect of emotional-painful stress (EPS) and experimental myocardial infarction on portal vein contractile function, adrenoreactivity , and resistance to the glucose shortage was studied on the rat. The myocardial infarction was shown to result in shifts of the smooth muscle contractile function which were similar to those in EPS, though being somewhat less pronounced. These changes included depressed spontaneous contractility, reduced adrenoreactivity and decreased resistance to the shortage of glucose in the washing solution. Preliminary administration of membrane protectors, the antioxidant ionol and nicotinamid , a lipase inhibitor, prevents such post-stress disturbances to a considerable degree.