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[情绪性疼痛应激对门静脉收缩功能对钙浓度变化的抵抗作用及缺氧的影响]

[Effect of an emotionally painful stress on the resistance of the portal vein contractile function to changes in calcium concentration and the effect of anoxia].

作者信息

Meerson F Z, Manukhina E B, Pinelis V G

出版信息

Biull Eksp Biol Med. 1983 Oct;96(10):12-4.

PMID:6684959
Abstract

The effect of acute anoxia and different concentrations of calcium in the washing solution on spontaneous contractility of isolated portal vein was studied in control and stress-exposed rats. Emotional painful stress resulted in a decrease of vascular smooth muscle resistance to anoxia and in an increase of its sensitivity to the changes of calcium concentrations in the environment. These changes are assumed to be the result of the stress-induced disturbance of energy supply to the myofibrillar contractile apparatus and of the damaged membranous mechanisms of calcium transport.

摘要

在对照大鼠和应激暴露大鼠中,研究了急性缺氧以及冲洗液中不同钙浓度对离体门静脉自发收缩性的影响。情绪性疼痛应激导致血管平滑肌对缺氧的耐受性降低,以及对环境中钙浓度变化的敏感性增加。这些变化被认为是应激诱导的肌原纤维收缩装置能量供应紊乱以及钙转运膜机制受损的结果。

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Disturbance of contractile function of vena portae in stress and infarction and its prevention.
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