Holmes D R, Vlietstra R E, Smith H C, Vetrovec G W, Kent K M, Cowley M J, Faxon D P, Gruentzig A R, Kelsey S F, Detre K M
Am J Cardiol. 1984 Jun 15;53(12):77C-81C. doi: 10.1016/0002-9149(84)90752-5.
The results of follow-up angiography in patients from 27 clinical centers enrolled in the PTCA Registry were analyzed to evaluate restenosis after PTCA. Of 665 patients with successful PTCA, 557 (84%) had follow-up angiography (median follow-up 188 days). Restenosis, defined as an increase of at least 30% from the immediate post-PTCA stenosis to the follow-up stenosis or a loss of at least 50% of the gain achieved at PTCA, was seen in 187 patients (33.6%). The incidence of restenosis in patients who underwent follow-up angiography was highest within the first 5 months after PTCA. Restenosis was found in 56% of patients with definite or probable angina after PTCA and in 14% of patients without angina after PTCA. Twenty-four percent of patients with restenosis did not have either definite or probable angina. Multivariate analysis selected 4 factors associated with increased rate of restenosis: male sex, PTCA of bypass graft stenosis, severity of angina before PTCA and no history of MI before PTCA.
对参加PTCA注册研究的27个临床中心的患者进行随访血管造影的结果进行分析，以评估PTCA术后再狭窄情况。在665例PTCA成功的患者中，557例（84%）接受了随访血管造影（中位随访时间188天）。187例患者（33.6%）出现再狭窄，定义为从PTCA术后即刻狭窄到随访时狭窄至少增加30%，或丧失PTCA时获得增益的至少50%。接受随访血管造影的患者中，再狭窄发生率在PTCA术后前5个月内最高。PTCA术后有明确或可能心绞痛的患者中56%出现再狭窄，PTCA术后无心绞痛的患者中14%出现再狭窄。24%的再狭窄患者既无明确也无可能心绞痛。多因素分析选出与再狭窄发生率增加相关的4个因素：男性、旁路移植血管狭窄的PTCA、PTCA术前心绞痛严重程度以及PTCA术前无心肌梗死病史。
