Broggini M, Maggiolo F, Bianchi E, Torre D
Boll Ist Sieroter Milan. 1983;62(6):495-500.
This study is a longitudinal epidemiologic survey (January 1980--December 1982) of hepatitis B virus (HBV) markers in an institution for subnormal people (62 patients--25 mentally retarded, 15 suffering from epilepsy, 15 from Down's syndrome, 7 from other diseases--and 23 nuns), in order to assess the prevalence and incidence of hepatitis B and the annual rate of seroconversion for HBV markers and to verify the efficacy of hygienic and prophylactic measures, that we adopted. Our data confirmed the efficacy of these measures, showing a significant decrease of HBsAg positive subjects and a parallel significant positivization of HBsAb positive subjects.
本研究是一项针对一所智障人士机构（62名患者——25名智力障碍者、15名癫痫患者、15名唐氏综合征患者、7名患有其他疾病者以及23名修女）进行的关于乙型肝炎病毒（HBV）标志物的纵向流行病学调查（1980年1月至1982年12月），目的是评估乙型肝炎的患病率和发病率、HBV标志物的年血清学转换率，并验证我们所采取的卫生和预防措施的效果。我们的数据证实了这些措施的有效性，显示HBsAg阳性受试者显著减少，同时HBsAb阳性受试者相应地显著增多。
