犬GM2神经节苷脂沉积症：化学和酶学特征。
Canine GM2-gangliosidosis: chemical and enzymatic features.
作者信息
Eto Y, Autilio-Gambetti L, McGrath J T
出版信息
Adv Exp Med Biol. 1984;174:431-40. doi: 10.1007/978-1-4684-1200-0_36.
PMID:6234761
Abstract
The chemical and enzymatic features in tissues of GM2-gangliosidosis are characterized by the analysis of glycolipids and FD-MS, and also by enzymatic analysis with DEAE-Sepharose column chromatography. The results suggest that canine GM2-gangliosidosis is equivalent to human juvenile GM2-gangliosidosis.
摘要
通过对糖脂和场解吸质谱（FD-MS）的分析，以及采用二乙氨基乙基琼脂糖凝胶柱色谱法进行酶分析，对GM2神经节苷脂沉积症组织中的化学和酶学特征进行了表征。结果表明，犬GM2神经节苷脂沉积症等同于人类青少年GM2神经节苷脂沉积症。
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