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Ligand-induced conformations of rat brain hexokinase: studies with hexoses, hexose 6-phosphates, and nucleoside triphosphates leading to development of a new model for the enzyme.

作者信息

Wilson J E

出版信息

Arch Biochem Biophys. 1978 Jan 15;185(1):88-99. doi: 10.1016/0003-9861(78)90147-9.

DOI:10.1016/0003-9861(78)90147-9
PMID:623494
Abstract
摘要

相似文献

1
Ligand-induced conformations of rat brain hexokinase: studies with hexoses, hexose 6-phosphates, and nucleoside triphosphates leading to development of a new model for the enzyme.配体诱导的大鼠脑己糖激酶构象:利用己糖、6-磷酸己糖和三磷酸核苷进行的研究,从而建立该酶的新模型。
Arch Biochem Biophys. 1978 Jan 15;185(1):88-99. doi: 10.1016/0003-9861(78)90147-9.
2
Ligand-induced conformational changes of rat brain hexokinase: their role in determining the substrate specificity for hexoses and inhibitory effectiveness of hexose 6-phosphates.
Arch Biochem Biophys. 1979 Aug;196(1):79-87. doi: 10.1016/0003-9861(79)90553-8.
3
Studies on the uptake of hexose phosphates. I. 2-Deoxyglucose and 2-deoxyglucose 6-phosphate.己糖磷酸摄取的研究。I. 2-脱氧葡萄糖和6-磷酸-2-脱氧葡萄糖
J Biol Chem. 1971 May 10;246(9):2881-4.
4
Brain hexokinase has two spatially discrete sites for binding of glucose-6-phosphate.
J Biol Chem. 1980 Aug 25;255(16):7548-51.
5
Effect of ligand binding on the tryptic digestion pattern of rat brain hexokinase: relationship of ligand-induced conformational changes to catalytic and regulatory functions.配体结合对大鼠脑己糖激酶胰蛋白酶消化模式的影响:配体诱导的构象变化与催化和调节功能的关系。
Arch Biochem Biophys. 1991 Nov 15;291(1):59-68. doi: 10.1016/0003-9861(91)90105-r.
6
Rat brain hexokinase: further studies on the specificity of the hexose and hexose 6-phosphate binding sites.大鼠脑己糖激酶:对己糖及6-磷酸己糖结合位点特异性的进一步研究
Arch Biochem Biophys. 1989 Mar;269(2):517-25. doi: 10.1016/0003-9861(89)90135-5.
7
Binding of nucleoside triphosphates, inorganic phosphate, and other polyanionic ligands to the N-terminal region of rat brain hexokinase: relationship to regulation of hexokinase activity by antagonistic interactions between glucose 6-phosphate and inorganic phosphate.
Arch Biochem Biophys. 1990 Feb 15;277(1):26-34. doi: 10.1016/0003-9861(90)90545-a.
8
[Electroretinographic and neurochemical observations with 2-deoxyglucose and glucose-6-phosphate].
Ann Ottalmol Clin Ocul. 1967 Jan;93(1):19-30.
9
Isolation and characterization of the discrete N- and C-terminal halves of rat brain hexokinase: retention of full catalytic activity in the isolated C-terminal half.大鼠脑己糖激酶离散的N端和C端片段的分离与特性分析:分离得到的C端片段保留完全催化活性
Arch Biochem Biophys. 1989 Nov 1;274(2):375-93. doi: 10.1016/0003-9861(89)90451-7.
10
Studies on the uptake of hexose phosphates. 3. Mechanism of uptake of glucose 1-phosphate in Escherichia coli.己糖磷酸摄取的研究。3. 大肠杆菌中1-磷酸葡萄糖的摄取机制。
J Biol Chem. 1971 May 10;246(9):2891-7.

引用本文的文献

1
Molecular forms of red blood cell hexokinase.红细胞己糖激酶的分子形式。
Mol Cell Biochem. 1982 Dec 10;49(3):129-42. doi: 10.1007/BF00231174.
2
Enzymes of glucose metabolism in cultured human gliomas: neoplasia is accompanied by altered hexokinase, phosphofructokinase, and glucose-6-phosphate dehydrogenase levels.培养的人脑胶质瘤中葡萄糖代谢的酶:肿瘤形成伴随着己糖激酶、磷酸果糖激酶和葡萄糖-6-磷酸脱氢酶水平的改变。
Metab Brain Dis. 1987 Mar;2(1):17-30. doi: 10.1007/BF00999506.