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Brain hexokinase has two spatially discrete sites for binding of glucose-6-phosphate.

作者信息

Lazo P A, Sols A, Wilson J E

出版信息

J Biol Chem. 1980 Aug 25;255(16):7548-51.

PMID:7400131
Abstract
摘要

相似文献

1
Brain hexokinase has two spatially discrete sites for binding of glucose-6-phosphate.
J Biol Chem. 1980 Aug 25;255(16):7548-51.
2
Ligand-induced conformational changes of rat brain hexokinase: their role in determining the substrate specificity for hexoses and inhibitory effectiveness of hexose 6-phosphates.
Arch Biochem Biophys. 1979 Aug;196(1):79-87. doi: 10.1016/0003-9861(79)90553-8.
3
Rat brain hexokinase: further studies on the specificity of the hexose and hexose 6-phosphate binding sites.大鼠脑己糖激酶：对己糖及6-磷酸己糖结合位点特异性的进一步研究
Arch Biochem Biophys. 1989 Mar;269(2):517-25. doi: 10.1016/0003-9861(89)90135-5.
4
Studies on the mode of sugar-phosphate product inhibition of brain hexokinase.脑己糖激酶的糖磷酸产物抑制模式研究。
Arch Biochem Biophys. 1976 Dec;177(2):480-7. doi: 10.1016/0003-9861(76)90459-8.
5
Binding of nucleoside triphosphates, inorganic phosphate, and other polyanionic ligands to the N-terminal region of rat brain hexokinase: relationship to regulation of hexokinase activity by antagonistic interactions between glucose 6-phosphate and inorganic phosphate.
Arch Biochem Biophys. 1990 Feb 15;277(1):26-34. doi: 10.1016/0003-9861(90)90545-a.
6
Ligand-induced conformations of rat brain hexokinase: studies with hexoses, hexose 6-phosphates, and nucleoside triphosphates leading to development of a new model for the enzyme.配体诱导的大鼠脑己糖激酶构象：利用己糖、6-磷酸己糖和三磷酸核苷进行的研究，从而建立该酶的新模型。
Arch Biochem Biophys. 1978 Jan 15;185(1):88-99. doi: 10.1016/0003-9861(78)90147-9.
7
[Electroretinographic and neurochemical observations with 2-deoxyglucose and glucose-6-phosphate].
Ann Ottalmol Clin Ocul. 1967 Jan;93(1):19-30.
8
Brain hexokinase has no preexisting allosteric site for glucose 6-phosphate.脑己糖激酶没有预先存在的用于6-磷酸葡萄糖的别构位点。
J Biol Chem. 1988 Oct 25;263(30):15492-7.
9
Rat brain hexokinase: location of the allosteric regulatory site in a structural domain at the N-terminus of the enzyme.
Arch Biochem Biophys. 1987 Dec;259(2):402-11. doi: 10.1016/0003-9861(87)90506-6.
10
A study of the sulfhydryl groups of rat brain hexokinase.大鼠脑己糖激酶巯基基团的研究。
Arch Biochem Biophys. 1974 Jul;163(1):191-9. doi: 10.1016/0003-9861(74)90469-x.

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1
Involvement of porin N,N-dicyclohexylcarbodiimide-reactive domain in hexokinase binding to the outer mitochondrial membrane.孔蛋白N，N-二环己基碳二亚胺反应结构域参与己糖激酶与线粒体外膜的结合。
Protein J. 2005 Jan;24(1):1-8. doi: 10.1007/s10930-004-0600-2.
2
Bovine hexokinase type I: full-length cDNA sequence and characterisation of the recombinant enzyme.牛I型己糖激酶：全长cDNA序列及重组酶的特性分析
Mol Cell Biochem. 2005 Jan;268(1-2):9-18. doi: 10.1007/s11010-005-1846-5.
3
Enzymatic properties of overexpressed human hexokinase fragments.
过表达的人己糖激酶片段的酶学性质
Mol Cell Biochem. 1998 Dec;189(1-2):185-93. doi: 10.1023/a:1006962217495.
4
Different properties of the mitochondrial and cytosolic hexokinases in maize roots.玉米根中线粒体和胞质己糖激酶的不同特性。
Biochem J. 1995 Jul 1;309 ( Pt 1)(Pt 1):105-12. doi: 10.1042/bj3090105.
5
A recombinant human 'mini'-hexokinase is catalytically active and regulated by hexose 6-phosphates.
Biochem J. 1992 Jul 1;285 ( Pt 1)(Pt 1):193-9. doi: 10.1042/bj2850193.