Haissaguerre M, Fleury B, Le Metayer P, Gabinski C, Conri C, Couzigou P, Warin J F, Blanchot P
Presse Med. 1984 Jul 7;13(28):1723-6.
Following acute intoxication with alcohol, 8 patients developed 16 episodes of arrhythmia, including 15 supraventricular tachycardias and one torsade de pointe. Seven of the 8 patients were chronically abusing of alcoholic drinks. None of the patients had clinically obvious cardiac pathology nor echocardiographic evidence of myocardiopathy. In 7 of them, however, baseline electrocardiograms disclosed disorders of intra-atrial conduction. The role of the different factors which might determine the occurrence of arrhythmia (notably alcohol, the autonomic nervous system, associated metabolic abnormalities and absorption of medicines) is discussed.
8名患者在急性酒精中毒后出现了16次心律失常发作,其中包括15次室上性心动过速和1次尖端扭转型室速。8名患者中有7名长期酗酒。所有患者均无明显的临床心脏病变,也没有心肌病的超声心动图证据。然而,其中7名患者的基线心电图显示存在心房内传导障碍。本文讨论了可能决定心律失常发生的不同因素(尤其是酒精、自主神经系统、相关代谢异常和药物吸收)的作用。