Houssin D, Pla M
Presse Med. 1984 Jul 7;13(28):1734-8.
Several experimental data suggest that, compared with other organs, the liver has a privileged status as concerns rejection. In fact, in pigs and rats, spontaneously tolerated liver allografts have been observed with, in rats, constitution of a state of donor-specific transplantation tolerance. Hyperacute rejection, which is a complication of organ allografts in some immunological situations, has not been observed after liver transplantation. In man, acute rejection of liver allografts usually is easily controlled by the immunosuppressive treatment. However, in some cases, an irreversible chronic rejection may occur.
多项实验数据表明，与其他器官相比，肝脏在排斥反应方面具有特殊地位。事实上，在猪和大鼠中，已观察到肝脏同种异体移植可自发耐受，在大鼠中还形成了供体特异性移植耐受状态。超急性排斥反应是某些免疫情况下器官同种异体移植的一种并发症，但肝移植后尚未观察到这种情况。在人类中，肝移植的急性排斥反应通常很容易通过免疫抑制治疗得到控制。然而，在某些情况下，可能会发生不可逆的慢性排斥反应。
