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[从神经学角度对早老性痴呆的鉴别诊断]

[Differential diagnosis of presenile dementia from the neurological viewpoint].

作者信息

Sommer I

出版信息

Z Alternsforsch. 1984 May-Jun;39(3):143-9.

PMID:6235680
Abstract

The author shows that dementia does not exist as a disease as such. Therefore, efforts in terms of differential diagnostics are required to investigate this psychopathological syndrome which may conceal a number of clinical pictures which are easy to treat or manifest themselves as dementia. If a patient suffers from dementia, the physician must not give in to diagnostic and therapeutical nihilism. Diagnosing the existence of dementia is just as inadequate as diagnosing the existence of a shoulder-hand syndrome. The reasons must be found and a number of advanced invasive and non-invasive methods are available today such as ultrasonography, computer tomography, measurements of the regional blood supply of the brain, angiography, electroencephalograms, laboratory tests, etc. Although all these advanced methods exist, a careful anamnesis and the clinical findings continue to be of significance for the aetiology of the disease. The author does not mention very rare diseases such as the group of leucodystrophies and subacute sclerosing panencephalitis, nor does he refer to diseases such as Whipple's disease, Creutzfeldt-Jakob disease, vitamin deficiencies and hormonal conditions, which may also accompany dementia.

摘要

作者指出,痴呆本身并非作为一种疾病而存在。因此,需要通过鉴别诊断来研究这种可能掩盖多种易于治疗或表现为痴呆的临床症状的精神病理综合征。如果患者患有痴呆,医生绝不能陷入诊断和治疗虚无主义。诊断痴呆的存在与诊断肩手综合征的存在一样不充分。必须找出原因,如今有许多先进的有创和无创方法,如超声检查、计算机断层扫描、脑局部血液供应测量、血管造影、脑电图、实验室检查等。尽管有所有这些先进方法,但仔细的病史采集和临床检查结果对于疾病的病因仍具有重要意义。作者未提及非常罕见的疾病,如脑白质营养不良症和亚急性硬化性全脑炎,也未提及可能伴随痴呆的疾病,如惠普尔病、克雅氏病、维生素缺乏症和激素状况。

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