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硬膜外注射局部麻醉药和皮质类固醇对腰腿痛患者的影响。

The effects of epidural injection of local anesthetics and corticosteroids on patients with lumbosciatic pain.

作者信息

Berman A T, Garbarino J L, Fisher S M, Bosacco S J

出版信息

Clin Orthop Relat Res. 1984 Sep(188):144-51.

PMID:6236001
Abstract

Although epidural cortisone injections are commonly used for treatment of lumbosciatic pain, insufficient critical analysis of the end result can be found in the literature. The present study is a retrospective critical analysis of 367 patients with leg pain who were engaged for a minimum of two weeks or an average of two months in multifaceted conservative management without relief of pain. Injections of 10 cm3 of 0.5% bupivacaine and 100 mg of methylprednisolone were given to inpatients treated by the same anesthesiologist. The average follow-up period was 21.4 months (range, 6-36 months). Results were analyzed according to duration of pain and history of prior lumbar spine surgery. The most favorable results (approaching 70% offd-excellent) were observed in patients with subacute radicular leg pain (of less than three months' duration) and chronic leg pain (of greater than three months' duration) with no prior surgery. Negative myelograms and electromyograms (EMGs), in the absence of reflex or motor deficits on physical examination, also pointed toward optimal results. Those patients with chronic pain who had had prior lumbar spine surgery had the least satisfactory results.

摘要

尽管硬膜外注射皮质类固醇常用于治疗腰腿痛,但文献中对最终结果的批判性分析不足。本研究是对367例腿痛患者的回顾性批判性分析,这些患者接受了至少两周或平均两个月的多方面保守治疗但疼痛未缓解。由同一位麻醉医生对住院患者注射10立方厘米0.5%布比卡因和100毫克甲基强的松龙。平均随访期为21.4个月(范围6 - 36个月)。根据疼痛持续时间和既往腰椎手术史分析结果。在无既往手术史的亚急性根性腿痛(持续时间少于三个月)和慢性腿痛(持续时间大于三个月)患者中观察到最有利的结果(接近70%为优 - 良)。在体格检查无反射或运动功能障碍的情况下,阴性脊髓造影和肌电图(EMG)也表明结果最佳。那些有慢性疼痛且既往有腰椎手术史的患者结果最不理想。

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