Tegtmeyer C J, Kellum C D, Ayers C
Radiology. 1984 Oct;153(1):77-84. doi: 10.1148/radiology.153.1.6236477.
Percutaneous transluminal angioplasty (PTA) was used to treat 109 patients with 141 renal artery stenoses, including 58 patients in whom medical management was unsuccessful. The initial success rate was 94%. Fifty-five patients had severe diffuse atherosclerosis and 40 had renal insufficiency. Thus far, 36 patients (50 stenoses) have undergone a total of 52 follow-up angiographic studies. Clinical data, including blood pressure response, were obtained in all cases. Only 7 of the 98 hypertensive patients failed to respond to PTA. Of the 11 patients treated primarily for renal insufficiency, 5 improved. Of the 29 hypertensive patients who also had elevated BUN and creatinine, renal function improved in 13. Altogether, 96 patients (88%) benefited from the procedure. Analysis of long-term results suggests that PTA should be the treatment of choice for fibromuscular dysplasia and short, segmental atherosclerotic lesions and could also prove helpful in improving renal insufficiency.
经皮腔内血管成形术(PTA)用于治疗109例患有141处肾动脉狭窄的患者,其中包括58例药物治疗无效的患者。初始成功率为94%。55例患者患有严重弥漫性动脉粥样硬化,40例患者存在肾功能不全。到目前为止,36例患者(50处狭窄)共接受了52次随访血管造影研究。所有病例均获取了包括血压反应在内的临床数据。98例高血压患者中只有7例对PTA无反应。在主要因肾功能不全接受治疗的11例患者中,5例病情有所改善。在29例同时伴有血尿素氮和肌酐升高的高血压患者中,13例肾功能得到改善。总体而言,96例患者(88%)从该手术中获益。长期结果分析表明,PTA应作为纤维肌性发育异常和短节段动脉粥样硬化病变的首选治疗方法,并且在改善肾功能不全方面也可能被证明是有帮助的。