Grützmacher P, Bussmann W D
Klin Wochenschr. 1986 Sep 15;64(18):884-96. doi: 10.1007/BF01725562.
The development of percutaneous transluminal techniques has brought up new possibilities for causative treatment of renovascular hypertension. In renal artery stenosis transluminal angioplasty is meanwhile routinely applied; experience with angioplasty to date exceeds by far the number of 1000 published cases. Technical success is obtained in more than 90%. The clinical success in the therapy of reno-vascular hypertension is approximately 76% over all with nearly equal cure and improvement rates. In fibromuscular stenosis clinical success has been obtained in 95% with a cure rate of 56% and improval in 39%. The cure rate is particularly low in patients with atherosclerotic stenosis with 19%, however in 60% improvement has been obtained, resulting in clinical benefit in 79%. Results obtained by surgery seem to be superior to those of dilatation, especially with regard to cure rates. However, the differences are minor and are compensated by the evident advantages of transluminal dilatation, especially its easy application and lower risk. Thus, 8 years after its introduction in nephrology, transluminal dilatation is the therapy of choice in renal artery stenosis. Other nonoperative interventional techniques, including transcatheter aspiration and embolectomy, intraarterial thrombolysis, embolisation and modified angioplasty provided valuable alternatives to usual surgical therapy. However, experience with some of these procedures is still limited. The complication rate of transluminal angioplasty of 10-20%, necessitating surgery in nearly 5%, prohibits its uncritical use.
经皮腔内技术的发展为肾血管性高血压的病因治疗带来了新的可能性。在肾动脉狭窄中,腔内血管成形术目前已常规应用;迄今为止血管成形术的经验远远超过已发表的1000例病例数。技术成功率超过90%。肾血管性高血压治疗的临床成功率总体约为76%,治愈率和改善率几乎相等。在纤维肌性狭窄中,临床成功率为95%,治愈率为56%,改善率为39%。动脉粥样硬化性狭窄患者的治愈率特别低,为19%,但改善率为60%,临床受益率为79%。手术获得的结果似乎优于扩张术,尤其是在治愈率方面。然而,差异很小,且被腔内扩张术的明显优势所抵消,尤其是其操作简便和风险较低。因此,腔内扩张术在肾脏病学中应用8年后,已成为肾动脉狭窄的首选治疗方法。其他非手术介入技术,包括经导管抽吸和栓子切除术、动脉内溶栓、栓塞和改良血管成形术,为常规手术治疗提供了有价值的替代方法。然而,其中一些手术的经验仍然有限。腔内血管成形术的并发症发生率为10 - 20%,近5%的患者需要手术,这限制了其不加选择的使用。