Jacobs J C, Pesce M
Arthritis Rheum. 1978 Jan-Feb;21(1):129-32. doi: 10.1002/art.1780210120.
A micromethod has been developed for determination of plasma salicylate. Frequent determinations of plasma salicylate levels in children with juvenile rheumatoid arthritis may be expected to provide greater therapeutic efficacy with reduced incidence of aspirin toxicity and consequently less need for use of secondary, more toxic, agents.
已开发出一种微量法用于测定血浆水杨酸盐。预计对青少年类风湿性关节炎患儿频繁测定血浆水杨酸盐水平,可提高治疗效果,降低阿司匹林毒性发生率,从而减少使用毒性更强的二线药物的必要性。