Block B S, Parer J T, Court D J, Llanos A J
Am J Obstet Gynecol. 1984 Oct 15;150(4):406-8. doi: 10.1016/s0002-9378(84)80148-9.
A microcomputer-based system has been developed to measure oxygen consumption continuously in fetal sheep. The system includes an umbilical artery electromagnetic blood flow transducer and two fiberoptic catheter oximeters for measuring umbilical artery and vein oxyhemoglobin saturation in vivo. The electrical signals from these instruments are digitized and sampled by a microcomputer. Fetal oxygen consumption is calculated from the Fick principle by use of the digitized signals and hemoglobin concentrations. The latter is measured intermittently and updated if necessary. System validation required that artifacts in oxyhemoglobin recordings could be avoided and that the catheter readings agreed with values from intermittent samples. Continuous heparin infusion and careful catheter placement facilitated attainment of these requirements. The system can be used to obtain continuous recordings of fetal oxygen consumption during rapidly occurring physiologic events.
已开发出一种基于微型计算机的系统，用于连续测量胎羊的耗氧量。该系统包括一个脐动脉电磁血流传感器和两个光纤导管血氧计，用于在体内测量脐动脉和静脉的氧合血红蛋白饱和度。这些仪器发出的电信号由微型计算机进行数字化和采样。胎儿耗氧量根据菲克原理，利用数字化信号和血红蛋白浓度进行计算。血红蛋白浓度是间歇性测量的，必要时进行更新。系统验证要求避免氧合血红蛋白记录中的伪迹，并且导管读数与间歇性样本的值一致。持续输注肝素和小心放置导管有助于满足这些要求。该系统可用于在快速发生的生理事件期间获取胎儿耗氧量的连续记录。
