Klinger M, Halbhuber K J
Biomed Biochim Acta. 1984;43(6):S88-90.
The IgG receptor expression on the membrane of the erythrocytes (RBC) during in vitro ageing was tested by means of a macrophage-RBC-endocytosis technique. The objects were: NaF-treated, glucose-free incubated and vesiculating RBC. The experiments show that unmasking of IgG receptor sites can be attributed to membrane conformational changes caused by ATP depletion of the cells. Vesiculation processes and (endogenous) enzymatically produced breakdown of glycoocalyx components are probably not related to increased IgG binding of aged RBC.
采用巨噬细胞-红细胞内吞技术检测体外老化过程中红细胞（RBC）膜上IgG受体的表达。研究对象为：经NaF处理、无糖孵育和形成囊泡的红细胞。实验表明，IgG受体位点的暴露可归因于细胞ATP耗竭引起的膜构象变化。囊泡形成过程和（内源性）酶促导致的糖萼成分分解可能与老化红细胞IgG结合增加无关。
