Voyer M, Valleur D, Belloy C, Salbreux R, Hyon-Jomier M, Terrier F, Charlas J
Arch Fr Pediatr. 1984 Oct;41(8):533-9.
The outcome of 404 prematures born before 32 weeks of gestation and admitted on the first day of life to the Institut de Puériculture (IP) in 1978-1980 was studied with respect to post-menstrual age and birth weight: 83 (20,5%) died during the hospitalization. Of the 321 still alive after the neonatal hospitalization, 71% were followed until at least 2 years of age; 3,1% died unexpectedly at home. There was a 8% handicap rate (9 with cerebral palsy and 9 with psychomotor deficiency) in the survivors. The problems of the children without handicap consisted mostly of strabismus and psychosocial disturbances. Thus, on admission to the IP on the first day of life during 1978-1980, according to gestational age (a) less than 28 weeks, (b) between 28 and 29 weeks 6 days (c) between 30 and 31 weeks 6 days, a premature presented the following risks: death during hospitalization: (a) 47%, (b) 20% and (c) 15%; death at home (b) 5%, (c) 1%; handicap (a) 3%, (b) 10%, (c) 5%; normal survival (a) 47%, (b) 63%, (c) 75%. This study shows the value of gestational age in estimating the outcome of prematures and the utility of analysing the results according to the 2 variables of gestational age and birth weight.
对1978 - 1980年间在法国儿童教养院(IP)出生后第一天入院的404名孕32周前早产的婴儿,按照孕龄和出生体重进行了预后研究:83名(20.5%)在住院期间死亡。在新生儿住院后仍存活的321名婴儿中,71%被随访至至少2岁;3.1%在家中意外死亡。存活者中有8%的致残率(9名患有脑瘫,9名有精神运动发育迟缓)。无残疾儿童的问题主要是斜视和心理社会障碍。因此,对于1978 - 1980年间出生后第一天入住IP的早产儿,根据孕龄(a)小于28周,(b)28至29周6天,(c)30至31周6天,呈现出以下风险:住院期间死亡:(a)47%,(b)20%,(c)15%;在家中死亡(b)5%,(c)1%;致残(a)3%,(b)10%,(c)5%;正常存活(a)47%,(b)63%,(c)75%。这项研究显示了孕龄在评估早产儿预后方面的价值,以及根据孕龄和出生体重这两个变量分析结果的实用性。