Barker G R
Br J Oral Maxillofac Surg. 1984 Dec;22(6):426-30. doi: 10.1016/0266-4356(84)90049-4.
The diagnosis of unifocal oral lymphomas is not easy and yet, a retrospective review of the malignancies diagnosed by the University of Birmingham Department of Oral Pathology, indicates that lymphoma is the third most commonly diagnosed malignant lesion in the oral cavity. In a separate study of all the cases of unifocal oral lymphomas which are recorded in the Birmingham and West Midland Cancer Registry for the period 1957-1976, lymphomas were found in the cheek, the lip, the tongue, the alveolus, the hard palate and soft palate, the gingival and oral mucosa overlying the buccal sulcus and in the salivary and mucous glands. The survival rates of patients with lymphomas underline the fact that the prognosis falls rapidly from the early stages where the lymphoma lesion is relatively small, single and isolated, to the later stage where there is also involvement of the associated lymph nodes.
单灶性口腔淋巴瘤的诊断并非易事，然而，对伯明翰大学口腔病理科诊断的恶性肿瘤进行回顾性研究表明，淋巴瘤是口腔中第三常见的恶性病变。在另一项对1957年至1976年期间记录在伯明翰和西米德兰兹癌症登记处的所有单灶性口腔淋巴瘤病例的研究中，发现淋巴瘤出现在脸颊、嘴唇、舌头、牙槽、硬腭和软腭、覆盖颊沟的牙龈和口腔黏膜以及唾液腺和黏液腺中。淋巴瘤患者的生存率突显了这样一个事实，即预后从淋巴瘤病变相对较小、单一且孤立的早期阶段迅速下降到伴有相关淋巴结受累的后期阶段。
