Das D K, Gulati A, Bhatt N C, Mandal A K, Khan V A, Bhambhani S
Institute of Cytology and Preventive Oncology, Maulana Azad Medical College, New Delhi, India.
Acta Cytol. 1993 May-Jun;37(3):333-42.
Forty-five patients with oral or pharyngeal swellings were subjected to fine needle aspiration cytology (FNAC) of the mucosal surface over eight years. The age of the patients ranged from 2 to 85 years. The male:female ratio was 25:20. The common sites of involvement were palate (16 cases), cheek (9), pharynx (7) and tonsillar/peritonsillar area (6). Tongue, maxilla, alveolus and lips were less frequently involved. FNAC played an important role in differentiating inflammatory from neoplastic lesions and also benign from malignant neoplasms. Fifteen cases were cytologically diagnosed as benign neoplasms and included pleomorphic adenoma (11 cases), schwannoma (2), odontogenic tumor (1) and benign neoplasm not otherwise specified (1). Sixteen cases were diagnosed as malignancies. There were seven cases of malignant salivary gland tumors and 6 of squamous cell carcinoma. Two cases were high grade non-Hodgkin's lymphomas, and one was malignant odontogenic tumor. Of the 11 inflammatory or reactive lesions, 4 were found to be harboring Actinomyces. The rate of inadequate sampling was 6.7%. Histopathology reports on excised tissue were available for 10 cases only. Seven of nine cases with adequate cytology (77.88%) showed complete agreement with histology.
在八年时间里，对45例口腔或咽部肿胀患者的黏膜表面进行了细针穿刺细胞学检查（FNAC）。患者年龄从2岁到85岁不等。男女比例为25:20。常见受累部位为腭部（16例）、颊部（9例）、咽部（7例）和扁桃体/扁桃体周围区域（6例）。舌、上颌骨、牙槽和唇部受累较少。FNAC在鉴别炎性病变与肿瘤性病变以及良性肿瘤与恶性肿瘤方面发挥了重要作用。15例经细胞学诊断为良性肿瘤，包括多形性腺瘤（11例）、神经鞘瘤（2例）、牙源性肿瘤（1例）和未另行指定的良性肿瘤（1例）。16例被诊断为恶性肿瘤。其中有7例恶性涎腺肿瘤和6例鳞状细胞癌。2例为高级别非霍奇金淋巴瘤，1例为恶性牙源性肿瘤。在11例炎性或反应性病变中，有4例发现含有放线菌。采样不足率为6.7%。仅10例有切除组织的组织病理学报告。9例细胞学检查充分的病例中有7例（77.88%）与组织学结果完全一致。
