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大脑正电子发射断层扫描:研究人类大脑病理生理学的新可能性。

Positron emission tomography of the brain: new possibilities for the investigation of human cerebral pathophysiology.

作者信息

Leenders K L, Gibbs J M, Frackowiak R S, Lammertsma A A, Jones T

出版信息

Prog Neurobiol. 1984;23(1-2):1-38. doi: 10.1016/0301-0082(84)90010-8.

Abstract

In the foregoing an overview of positron emission tomography has been presented. Its theoretical, technical, and methodological implications, as well as its clinical applications have been outlined. The emphasis has been on the quantitative aspects of the method and its usefulness is investigating normal and pathological functions of brain tissue. Although the potential of this new research technique is obvious, many theoretical and practical difficulties still need to be solved. Nevertheless it provides an opportunity to bridge the gap between basic experimental research and clinical medicine.

摘要

前文已对正电子发射断层扫描进行了概述。文中概述了其理论、技术和方法学意义,以及临床应用。重点在于该方法的定量方面及其在研究脑组织正常和病理功能中的实用性。尽管这项新研究技术的潜力显而易见,但仍有许多理论和实际困难有待解决。然而,它为弥合基础实验研究与临床医学之间的差距提供了一个契机。

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