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[遗传因素在慢性支气管炎发病机制中的作用]

[Role of the hereditary factor in the genesis of chronic bronchitis].

作者信息

Amatuni V G, Pirumian M S

出版信息

Ter Arkh. 1984;56(10):25-8.

PMID:6240790
Abstract

Comparison of proband concordance of the phenotypic correlation coefficients according to the proneness to disease derived on analysis of the groups of mono- and dizygote twins born in 1930-1959 in the city of Yerevan presenting with chronic non-obstructive and chronic obstructive bronchitis revealed a substantial role of hereditary factors in the development of these patterns of chronic bronchitis. The inheritance coefficients calculated on the basis of the data obtained for chronic non-obstructive and chronic obstructive bronchitis point to the contribution of genetic factors to chronic bronchitis proneness among the population of the city of Yerevan.

摘要

对1930年至1959年出生在埃里温市、患有慢性非阻塞性和慢性阻塞性支气管炎的单卵双胞胎和双卵双胞胎群体进行分析后得出疾病易感性,比较先证者表型相关系数的一致性,结果显示遗传因素在这些慢性支气管炎类型的发展中起重要作用。根据慢性非阻塞性和慢性阻塞性支气管炎获得的数据计算出的遗传系数表明,遗传因素对埃里温市人群慢性支气管炎易感性有影响。

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