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[遗传和环境因素在慢性支气管炎发生中的意义(一项双胞胎研究)]

[Significance of genetic and environmental factors in the occurrence of chronic bronchitis (a study of twins)].

作者信息

Amatuni V G, Pirumian M S

出版信息

Ter Arkh. 1986;58(1):88-91.

PMID:2938296
Abstract

A study of a sample of 47 pairs of twins with chronic bronchitis made it possible to determine a qualitative and quantitative role of hereditary factors in "exposure" to this disease. A lower inheritability ratio was revealed in chronic obstructive bronchitis as compared to chronic nonobstructive bronchitis indicating leading role of the environmental factors (smoking and industrial hazards) in the development of this type of the disease. The importance of these factors in the etiology of different types of chronic bronchitis is also confirmed.

摘要

一项对47对患有慢性支气管炎的双胞胎样本的研究,使得确定遗传因素在该疾病“易感性”方面的定性和定量作用成为可能。与慢性非阻塞性支气管炎相比,慢性阻塞性支气管炎的遗传度较低,这表明环境因素(吸烟和工业危害)在这类疾病的发展中起主导作用。这些因素在不同类型慢性支气管炎病因学中的重要性也得到了证实。

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