全脑缺血后麻醉剂对脑脊液离子成分的影响。
Effect of anaesthetic agents on the ionic composition of cerebrospinal fluid following total cerebral ischaemia.
作者信息
Wade J G, Sørenson S C
出版信息
Can Anaesth Soc J. 1978 Jan;25(1):20-5. doi: 10.1007/BF03006778.
PMID:624102
Abstract
Total cerebral ischaemia in rats caused a marked increase in the cisternal CSF potassium concentration but little change in CSF sodium or chloride concentration. The anaesthetic techniques studied (pentobarbitone, halothane/oxygen and nitrous oxide/oxygen/relaxant) did not effect the potassium increase following cerebral ischaemia. We conclude that the mechanism of barbiturate protection following cerebral ischaemia is different from that of hypothermia.
摘要
大鼠全脑缺血导致脑池脑脊液钾浓度显著升高，但脑脊液钠或氯浓度变化不大。所研究的麻醉技术（戊巴比妥、氟烷/氧气和氧化亚氮/氧气/肌肉松弛剂）对脑缺血后钾浓度的升高没有影响。我们得出结论，脑缺血后巴比妥类药物的保护机制与低温不同。
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