Bernoco D, Bernoco M, Ceppellini R, Poulik M D, Leeuwen A, Rood J J
Tissue Antigens. 1976 Oct;8(4):253-60.
A modification of the NIH cytotoxicity test for recognizing B cell (D-associated) antigens and antibodies, when sera also contain anti-HLA(ABC) activity is described. The method is based on the observation that anti-beta2-microglobulin reagents are able to block lympholysis only when due to HLA(ABC) antigens.
本文描述了一种对美国国立卫生研究院(NIH)细胞毒性试验的改良方法,用于识别B细胞(D相关)抗原和抗体,前提是血清中也含有抗HLA(ABC)活性。该方法基于以下观察结果:抗β2微球蛋白试剂只有在因HLA(ABC)抗原导致淋巴细胞溶解时才能阻断这种溶解。