Guerrin J, Fargeot P, de Gislain C, Mayer F, Rodriguez H, Massin F
Sem Hop. 1980;56(5-6):209-13.
To define prognostic factors of testicular cancer and to develop a strategic therapy based on clinical, pathological and biological findings, 77 cases of non seminomatous testis tumor, observed in G.F. Leclerc Center from 1967 to 1977, have been analysed. For all these patients early chemotherapy program was associated with surgery; radiation therapy was reserved for stages with retroperitoneal metastatic disease. Results of this review confirmed the interest of such medical treatment which improved survival in all stages of disease. Some prognostic factors could be detailed from these cases: nature of tumoral components, invading of lymph node, presence or not of biological markers; identification of these would unable us to choose the best adjuvant chemotherapy program and to define its place in the management of testis tumor's treatment.
为了确定睾丸癌的预后因素，并根据临床、病理和生物学检查结果制定策略性治疗方案，我们分析了1967年至1977年在G.F.勒克莱尔中心观察到的77例非精原细胞瘤性睾丸肿瘤。对所有这些患者，早期化疗方案与手术联合使用；放射治疗仅用于有腹膜后转移疾病的阶段。本综述结果证实了这种医学治疗的益处，它改善了疾病各阶段的生存率。从这些病例中可以详细阐述一些预后因素：肿瘤成分的性质、淋巴结侵犯情况、生物标志物的有无；确定这些因素将使我们能够选择最佳的辅助化疗方案，并确定其在睾丸肿瘤治疗管理中的地位。
