Osterhage H R, Jellinghaus W, Reichert H E
J Urol (Paris). 1982;88(2):97-9.
Over a ten year period, the authors have collected 120 cases of germinal tumours of the testis (35 seminomas and 85 non-seminomatous tumours). The largest single group was of mixed non-seminomatous tumours. The treatment of pure seminomas gave 100% good results by a combination of unilateral orchidectomy, radiotherapy and, in the case of stage III tumours with spread, chemotherapy. The prognosis of non-seminomatous tumours was dependent essentially upon the stage of spread. During the past three years, the best results of chemotherapy have been obtained with the combination of vincristin, bleomycin and platinum (1978, 1979, 1980). In his time, at stage I and stage II, all the patients are alive. Treatment consisted of a minimum of unilateral orchidectomy and retroperitoneal lymphadenectomy, Chemotherapy was envisaged only for those tumours with evidence of lymph node involvement. At stage III, they lost 3 patients out of 7, this being an excellent result bearing in mind the gravity of such tumours.
在十年期间，作者收集了120例睾丸生殖细胞瘤（35例精原细胞瘤和85例非精原细胞瘤）。最大的单一类别是混合性非精原细胞瘤。单纯精原细胞瘤通过单侧睾丸切除术、放射治疗以及对于有扩散的III期肿瘤采用化疗相结合的方法，取得了100%的良好效果。非精原细胞瘤的预后主要取决于扩散阶段。在过去三年中，长春新碱、博来霉素和铂联合使用（1978年、1979年、1980年）取得了最佳化疗效果。在当时，I期和II期的所有患者均存活。治疗至少包括单侧睾丸切除术和腹膜后淋巴结清扫术，仅对有淋巴结受累证据的肿瘤考虑进行化疗。在III期，7例患者中有3例死亡，考虑到此类肿瘤的严重性，这是一个非常好的结果。
