Gil R, Lefèvre J P
Sem Hop. 1980;56(5-6):214-20.
The study of the blink reflex, performed in a group of 33 patients with multiple sclerosis show, as Kimura (1970) and Namerow (1973) had established, the high frequency of its alterations in this disease (almost half of the cases). The alterations of blink reflex don't depend on duration of illness; if it is true that the alterations of blink reflex are more often observed in patients with clinical symptoms of involvement of brain-stem (and particularly of pons), in some cases, only the alteration of the blink reflex suggests a brain-stem's lesion and helps to establish the diagnosis. The diversity of sites of lesions induced by multiple sclerosis in the brain-stem explains the diversity of blink reflex alteration's syndromes since they correspond to the (almost) totality of the semiology of blink reflex.
对33例多发性硬化症患者进行的瞬目反射研究表明，正如木村（1970年）和纳梅罗（1973年）所证实的，该疾病中瞬目反射改变的发生率很高（几乎占病例的一半）。瞬目反射的改变与病程长短无关；诚然，瞬目反射的改变在有脑干（尤其是脑桥）受累临床症状的患者中更常被观察到，但在某些情况下，仅瞬目反射的改变就提示脑干病变并有助于确诊。多发性硬化症在脑干引起的病变部位的多样性解释了瞬目反射改变综合征的多样性，因为它们（几乎）与瞬目反射的全部症状学相对应。
