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Differential regulation of thyrotropin releasing hormone receptors in neoplastic rodent mammotropic, adrenocorticotropic and thyrotropic pituitary cells in culture.

作者信息

Peck V, Gershengorn M C

出版信息

J Clin Endocrinol Metab. 1980 Jun;50(6):1144-6. doi: 10.1210/jcem-50-6-1144.

DOI:10.1210/jcem-50-6-1144
PMID:6246145
Abstract

Modulation of the concentration of receptors for thyrotropin releasing hormone (TRH) is different in neoplastic mammotropic, adrenocorticotropic, and thyrotropic pituitary cells in culture. Hydrocortisone increases the TRH receptor concentration in mammotropic and adrenocorticotropic cells but has no effect in thyrotropic cells. B-estradiol increases the TRH receptor number in mammotropic cells but has no effect in adrenocorticotropic and thyrotropic cells. Both TRH and T3 decrease the receptor concentration in all three cell types.

摘要

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